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Showing all 42 items for (author: horn-ghetko & d)

EMDB-18214:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18216:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18217:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused on E2-like density
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18218:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused dimeric core
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18220:
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 CPH domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18221:
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 DOC domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18222:
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 ARM9 domain
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-18223:
Structure of the hexameric CUL9-RBX1 complex with deletion of CUL9 ARIH-RBR element
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

EMDB-19179:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Prabu JR, Schulman BA

PDB-8q7e:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

PDB-8q7h:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Schulman BA

PDB-8rhz:
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer
Method: single particle / : Hopf LVM, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-16355:
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16356:
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16865:
Tetrameric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-16866:
Cryo-EM map of ubiquitin-VME bound HECT E3 ligase UBR5
Method: single particle / : Hehl LA, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-16867:
Ubiquitin transfer from E2 to E3: UBE2D2-ubiquitin linked to HECT E3 ligase UBR5
Method: single particle / : Hehl LA, Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-17466:
Cryo-EM map of HECT E3 ligase UBR5 forming K48 linked ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

PDB-8c06:
Structure of Dimeric HECT E3 Ubiquitin Ligase UBR5
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

PDB-8c07:
Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
Method: single particle / : Hehl LA, Prabu JR, Schulman BA

EMDB-12995:
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Method: single particle / : Kostrhon SP, prabu JR, Schulman BA

EMDB-12998:
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3C (A3C fullcomplex consensus )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-12999:
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* ( A3G E3-E3 catalytic focused )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-13000:
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3C (A3C consensus )
Method: single particle / : Kostrhon SP, Prabu JR, Schulman BA

EMDB-13001:
Structure of Neddylated CRL5Vif-CBFbeta-ARIH2*-APOBEC3G ( A3G consensus )
Method: single particle / : Kostrhon SP, prabu JR, Schulman BA

PDB-7oni:
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Method: single particle / : Kostrhon SP, prabu JR, Schulman BA

EMDB-12040:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5m:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12004:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 ligase superassembly. NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1-UBE2L3~Ub. Pre-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12005:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1~Ub. post-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12006:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12036:
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12037:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12038:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12039:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12041:
Focused map-catalytic side. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12048:
Focused map- CyclinA-CDK2-class. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12050:
Focused map- Cullin scaffold. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5l:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5n:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5r:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5s:
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

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